Cancer Genetics Offers Oncomine Comprehensive Assay to Drive Clinical Trials
Published on: Thursday, September 20th, 2018 View all Media
RUTHERFORD, N.J., Sept. 20, 2018 (GLOBE NEWSWIRE) — Cancer Genetics, Inc. (Nasdaq: CGIX), a leader in enabling precision medicine for immuno-oncology and genomics through molecular markers and diagnostics, today announced the successful CLIA validation and commercial launch of Thermo Fisher Scientific’s next-generation sequencing (NGS) Oncomine™ Comprehensive Assay v3 for biopharma clinical trials.
John A. Roberts, Chief Executive Officer of Cancer Genetics, commented, “As we have previously announced, we are continuing to gain momentum with key channel partners. Oncomine™ Comprehensive Assay v3 provides confidence in understanding cancer mutations. This newest version of the assay supports both translational and clinical researchers with superior tumor profiling capabilities that enable reliable results. We are excited about the potential of the Oncomine Comprehensive Assay in drastically improving clinical oncology research.”
Oncomine Comprehensive Assay v3 features content based on the advances in clinical oncology research. It enables simultaneous analysis of DNA and RNA to detect hundreds of variant types, including single nucleotide variants (SNVs), copy number variations (CNVs), gene fusions, and indels from unique cancer driver genes, across 161 genes relevant to solid tumors.
It also covers the entire kinase domain in several critical receptor tyrosine kinases, which increases the likelihood of detecting functionally relevant mutations in addition to known actionable and prevalent variants. Additionally, the assay represents 31 genes involved in the DNA repair pathway and covers MAPK, PI3K, and cell cycle pathway genes.
Oncomine™ Comprehensive Assay v3 requires only 10 ng of DNA or RNA per pool to deliver analysis of even small and challenging formalin-fixed, paraffin-embedded (FFPE) samples. It is optimized for automated library preparation using the Ion Chef System and rapid sequencing on the Ion GeneStudio S5 Systems with analysis reporting using the Oncomine™ Knowledgebase Reporter, which aligns results with the most recent published evidence on clinical oncology research.
ABOUT CANCER GENETICS
Cancer Genetics, Inc. is a leader in enabling precision medicine in oncology from bench to bedside through the use of oncology biomarkers and molecular testing. CGI is developing a global footprint with locations in the US, Australia and China. We have established strong clinical research collaborations with major cancer centers such as Memorial Sloan Kettering, The Cleveland Clinic, Mayo Clinic, Keck School of Medicine at USC and the National Cancer Institute.
The Company offers a comprehensive range of laboratory services that provide critical genomic and biomarker information. Its state-of-the-art reference labs are CLIA-certified and CAP-accredited in the US and have licensure from several states including New York State.