Multi-Platform Approach to Genotyping

CGI provides high quality genotyping services for clinical trials, which adhere to stringent regulatory standards including GLP, CLIA, and GCP. Our strategy is to be “platform agnostic”, meaning that CGI is not dedicated to any one technology platform. The flexibility, scalability, and versatility, provided by a multi-platform approach, allow us to provide the best solution for a wide range of client needs. CGI’s scientific team works with clients to choose the clinically relevant genes and variants, providing them with customizable, attention-driven service.

Over the past 15 years, our portfolio has grown to over 400 validated, clinical genotyping assays. If an assay for a particular gene or polymorphism is not available, CGI has extensive experience in custom assay development and validation. We are a certified services provider for various companies such as Affymetrix, ArcherDx, etc… and offer full NGS capabilities with both Illumina and Thermo Fisher Platforms, providing a mix of proprietary panels and off-the-shelf assays.

To learn more about our capabilities, contact us for more information.

Summary of Genotyping Services

  • Single SNP to whole genome genotyping
  • Over 400 validated genotyping assays and growing; including Phase I and Phase II drug metabolizing enzymes, transporters, and receptors
  • 11 validated oncology focused NGS panels (disease-specific) and 2 comprehensive oncology panels
  • Whole exome sequencing/ Custom NGS panels
  • Customized pharmacogenomics (PGx) testing
  • CLIA grade testing for the FDA’s Pharmacogenomic Biomarkers in Drug Labels recommended panel
  • Liquid Biopsy: profiling of circulating tumor cells, cell-free and circulating tumor DNA (CTCs, cfDNA, ctDNA)
  • Human Leukocyte Antigen (HLA) allele calling
  • Loss of heterozygosity
  • Copy number variations (CNV)
  • Microsatellite/STR analysis
  • Microsatellite Instability (MSI)
  • Comprehensive bioinformatics
Available Genotyping Platforms

  • qPCR
  • Sanger Sequencing
  • NanoString

Next Generation Sequencing

  • Ion Torrent (Thermo Fisher)
  • Illumina

DNA Microarrays

  • DMET® Certified
  • Affymetrix whole genome
  • Custom arrays
  • Cytogenetic Copy Number